Transformative biomarkers for drug-induced liver injury: are we there yet?

Biomark Med. 2017 Feb;11(2):103-106. doi: 10.2217/bmm-2016-0338. Epub 2017 Jan 18.

Authors

Daniel J Antoine¹, James W Dear²

Affiliations

¹ Department of Molecular & Clinical Pharmacology & the MRC Centre for Drug Safety Science, University of Liverpool, Liverpool, UK.
² Pharmacology, Toxicology & Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.

PMID: 28097885
DOI: 10.2217/bmm-2016-0338

No abstract available

Keywords: DILI; HMGB1; hepatotoxicity; miR-122; paracetamol; qualification.

Publication types

Editorial

MeSH terms

Biomarkers / metabolism*
Biomarkers, Pharmacological / metabolism
Chemical and Drug Induced Liver Injury / diagnosis*
Chemical and Drug Induced Liver Injury / genetics
Chemical and Drug Induced Liver Injury / metabolism*
Humans

Substances

Biomarkers
Biomarkers, Pharmacological