Phenolic Compounds from the Leaves of Castanopsis fargesii

Yong-Lin Huang; Ya-Feng Wang; Jin-Lei Liu; Lei Wang; Takashi Tanaka; Yue-Yuan Chen; Feng-Lai Lu; Dian-Peng Li

doi:10.3390/molecules22010162

Phenolic Compounds from the Leaves of Castanopsis fargesii

Molecules. 2017 Jan 19;22(1):162. doi: 10.3390/molecules22010162.

Authors

Yong-Lin Huang¹, Ya-Feng Wang², Jin-Lei Liu³, Lei Wang⁴, Takashi Tanaka⁵, Yue-Yuan Chen⁶, Feng-Lai Lu⁷, Dian-Peng Li⁸

Affiliations

¹ Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. [email protected].
² Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. [email protected].
³ Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. [email protected].
⁴ Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. [email protected].
⁵ Department of Natural Product Chemistry, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan. [email protected].
⁶ Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. [email protected].
⁷ Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. [email protected].
⁸ Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China. [email protected].

Abstract

In the course of a phytochemical and chemotaxonomical investigation of Castanopsis species (Fagaceae), three new phenolic compounds, (3R,1'S)-[1'-(6″-O-galloyl-β-d-gluco-pyranosyl)oxyethyl]-3-hydroxy-dihydrofuran-2(3H)-one (1), (2R,3S)-2-[2'-(galloyl)oxyethyl]-dihydroxybutanoic acid (2), and (3S,4S)-3-hydroxymethyl-3,4-dihydro-5,6,7-trihydroxy-4-(4'-hydroxy-3'-methoxyphenyl)-1H-[2]-benzopyran-1-one (3) were isolated from the fresh leaves of Castanopsis fargesii. In addition, a known phenolic glycoside, gentisic acid 5-O-α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranoside (4) was also isolated and identified. Their structures were elucidated by means of spectroscopic methods including one- and two-dimensional NMR techniques.

Keywords: Castanopsis; Castanopsis fargesii; cytotoxicity; phenolic.

MeSH terms

Fagaceae / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Phenols / chemistry*
Plant Extracts / chemistry
Plant Leaves / chemistry*

Substances

Phenols
Plant Extracts