Higher vitreous concentrations of dabigatran after repeated oral administration

Acta Ophthalmol. 2017 Jun;95(4):e345-e346. doi: 10.1111/aos.13348. Epub 2017 Jan 27.

Authors

Verena C Mulder¹, Cornelis Kluft², Peter G van Etten³, Ellen C La Heij³, Jan C van Meurs^{1

3

4}

Affiliations

¹ Rotterdam Ophthalmic Institute, Rotterdam Eye Hospital, Rotterdam, The Netherlands.
² Good Biomarker Sciences, Leiden, The Netherlands.
³ Vitreoretinal Surgery, The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
⁴ Erasmus Medical Centre, Rotterdam, The Netherlands.

PMID: 28128536
DOI: 10.1111/aos.13348

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Aged, 80 and over
Antithrombins / administration & dosage
Antithrombins / pharmacokinetics
Blood-Retinal Barrier / drug effects*
Dabigatran / administration & dosage
Dabigatran / pharmacokinetics*
Dose-Response Relationship, Drug
Drug Administration Schedule
Female
Humans
Male
Retinal Perforations / drug therapy*
Retinal Perforations / metabolism
Tissue Distribution
Vitreous Body / metabolism*

Substances

Antithrombins
Dabigatran