PET+MR versus PET/CT in the initial staging of head and neck cancer, using a trimodality PET/CT+MR system

Tetsuro Sekine; Felipe de Galiza Barbosa; Felix P Kuhn; Irene A Burger; Paul Stolzmann; Gerhard F Huber; Spyros S Kollias; Gustav K von Schulthess; Patrick Veit-Haibach; Martin W Huellner

doi:10.1016/j.clinimag.2017.01.003

PET+MR versus PET/CT in the initial staging of head and neck cancer, using a trimodality PET/CT+MR system

Clin Imaging. 2017 Mar-Apr:42:232-239. doi: 10.1016/j.clinimag.2017.01.003. Epub 2017 Jan 17.

Affiliations

¹ Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland; Department of Radiology, Nippon Medical School, Tokyo, Japan. Electronic address: [email protected].
² Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland.
³ Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland; Clinic of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland.
⁴ Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland; Clinic of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland.
⁵ Department of Otorhinolaryngology, University Hospital Zurich, University of Zurich, Switzerland.
⁶ Clinic of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland.
⁷ Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Switzerland; Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland.

PMID: 28129606
DOI: 10.1016/j.clinimag.2017.01.003

Abstract

Purpose: To compare the diagnostic accuracy of PET+MR with PET/CT in the initial staging of head and neck cancer.

Materials and methods: Contrast-enhanced PET/CT+MR was performed in 27 patients with newly diagnosed head and neck cancer. PET/CT and PET+MR were evaluated separately, and the TNM stage and factors influencing treatment were assessed.

Results: The TNM staging by PET+MR was comparable to PET/CT (T: p=0.331, N: p=0.453, M: p=0.034). The sensitivity/specificity/accuracy of treatment-influencing factors by PET/CT and PET+MR were 0.68/0.99/0.97, and 1.00/1.00/0.99, respectively.

Conclusions: Whole-body staging with PET+MR yields at least equal diagnostic accuracy as PET/CT in head and neck cancer.

Keywords: ENT surgery; Head and neck cancer; Oncology; PET/CT; PET/MR.

MeSH terms

Adult
Aged
Aged, 80 and over
Female
Fluorodeoxyglucose F18
Head and Neck Neoplasms / diagnostic imaging*
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Multimodal Imaging
Neoplasm Staging
Positron Emission Tomography Computed Tomography*
Positron-Emission Tomography*
Prospective Studies
Radiopharmaceuticals
Sensitivity and Specificity

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18