ANAQUIN: a software toolkit for the analysis of spike-in controls for next generation sequencing

Bioinformatics. 2017 Jun 1;33(11):1723-1724. doi: 10.1093/bioinformatics/btx038.

Abstract

Summary: Spike-in controls are synthetic nucleic-acid sequences that are added to a user's sample and constitute internal standards for subsequent steps in the next generation sequencing workflow.

Availability and implementation: : The software is implemented in C ++/R and is freely available under BSD license. The source code is available from github.com/student-t/Anaquin , binaries and user manual from www.sequin.xyz/software and R package from bioconductor.org/packages/Anaquin.

Contact: [email protected] or [email protected].

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • High-Throughput Nucleotide Sequencing / methods*
  • Humans
  • Sequence Analysis, DNA / methods*
  • Sequence Analysis, RNA / methods*
  • Software*