Plants from Lamiaceae family as source of antifungal molecules in humane and veterinary medicine

Microb Pathog. 2017 Mar:104:232-237. doi: 10.1016/j.micpath.2017.01.050. Epub 2017 Jan 26.

Abstract

This work aimed to review the main plants of Lamiaceae family with activity against pathogenic fungi of medical and veterinary interest. Published studies in the main international databases between January 2002 and June 2016 showed that 55 botanical species belonging to 27 genus presented antifungal activity in different forms of extractions, mainly essential oils. Pathogenic fungi of Aspergillus spp., Candida spp., Malassezia spp., Cryptococcus spp., Sporothrix spp., Microsporum spp., Trichophyton spp. and Epidermophyton spp. genus were in vitro sensitive to several plants of Lamiaceae family. Chemical molecules isolated were described as promising use as antifungals in mycoses, highlighting estragole, 1,8-cineole, terpineol-4, γ-terpinene, among others. However, it should be alert to need of universal standardization in the laboratories tests with natural products.

Keywords: Antifungal resistance; Essential oils; Extracts; Mycosis; Natural products.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology
  • Antifungal Agents / therapeutic use*
  • Biological Products / isolation & purification
  • Biological Products / pharmacology
  • Biological Products / therapeutic use*
  • Fungi / drug effects*
  • Lamiaceae / chemistry*
  • Mycoses / drug therapy*
  • Mycoses / veterinary*
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology*

Substances

  • Antifungal Agents
  • Biological Products
  • Plant Extracts