Informed consent and clinical trials: where is the placebo effect?

C R Blease; F L Bishop; T J Kaptchuk

doi:10.1136/bmj.j463

Informed consent and clinical trials: where is the placebo effect?

BMJ. 2017 Feb 3:356:j463. doi: 10.1136/bmj.j463.

Authors

C R Blease^{1

2}, F L Bishop³, T J Kaptchuk²

Affiliations

¹ School of Philosophy, University College Dublin, Ireland [email protected].
² Program in Placebo Studies, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.
³ Department of Psychology, University of Southampton, UK.

Abstract

Lack of knowledge about placebos affects participants’ understanding of trials and breaches the ethical obligations of researchers, argue C R Blease, F L Bishop, and T J Kaptchuk

MeSH terms

Clinical Trials as Topic / ethics
Clinical Trials as Topic / psychology
Disclosure / ethics*
Ethics, Research
Humans
Informed Consent* / ethics
Informed Consent* / psychology
Patient Participation / psychology*
Patient Selection / ethics*
Placebo Effect*
Risk Assessment / ethics*

Grants and funding

R01 AT008573/AT/NCCIH NIH HHS/United States