Novel neurobiological roles of UBE3A

Oncotarget. 2017 Feb 21;8(8):12548-12549. doi: 10.18632/oncotarget.15105.
No abstract available

Keywords: Angelman syndrome; Neuroscience; UBE3A; mTORC1; synaptic plasticity; ubiquitination.

Publication types

  • Editorial

MeSH terms

  • Angelman Syndrome / metabolism
  • Animals
  • Autism Spectrum Disorder / metabolism
  • Endocytosis
  • Gene Expression Regulation
  • Hippocampus / metabolism
  • Humans
  • Mechanistic Target of Rapamycin Complex 1 / metabolism
  • Mechanistic Target of Rapamycin Complex 2 / metabolism
  • Mice
  • Protein Domains
  • Protein Kinase C-alpha / metabolism
  • Signal Transduction
  • TOR Serine-Threonine Kinases / metabolism
  • Ubiquitin-Protein Ligases / metabolism*

Substances

  • UBE3A protein, human
  • Ubiquitin-Protein Ligases
  • MTOR protein, human
  • Mechanistic Target of Rapamycin Complex 1
  • Mechanistic Target of Rapamycin Complex 2
  • TOR Serine-Threonine Kinases
  • Protein Kinase C-alpha