Image formation in diffusion MRI: A review of recent technical developments

J Magn Reson Imaging. 2017 Sep;46(3):646-662. doi: 10.1002/jmri.25664. Epub 2017 Feb 14.

Abstract

Diffusion magnetic resonance imaging (MRI) is a standard imaging tool in clinical neurology, and is becoming increasingly important for neuroscience studies due to its ability to depict complex neuroanatomy (eg, white matter connectivity). Single-shot echo-planar imaging is currently the predominant formation method for diffusion MRI, but suffers from blurring, distortion, and low spatial resolution. A number of methods have been proposed to address these limitations and improve diffusion MRI acquisition. Here, the recent technical developments for image formation in diffusion MRI are reviewed. We discuss three areas of advance in diffusion MRI: improving image fidelity, accelerating acquisition, and increasing the signal-to-noise ratio.

Level of evidence: 5 Technical Efficacy: Stage 1 J. MAGN. RESON. IMAGING 2017;46:646-662.

Keywords: accelerated imaging; diffusion MRI; high-resolution imaging; image artifacts; navigation; pulse sequence.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diffusion Magnetic Resonance Imaging / methods*
  • Humans
  • Image Enhancement / methods
  • Image Processing, Computer-Assisted / methods*
  • Signal-To-Noise Ratio