Severely frail elderly patients do not need lipid-lowering drugs

Laurie Herzig Mallery; Paige Moorhouse; Pam McLean Veysey; Michael Allen; Isobel Fleming

doi:10.3949/ccjm.84a.15114

Severely frail elderly patients do not need lipid-lowering drugs

Cleve Clin J Med. 2017 Feb;84(2):131-142. doi: 10.3949/ccjm.84a.15114.

Authors

Laurie Herzig Mallery¹, Paige Moorhouse², Pam McLean Veysey³, Michael Allen⁴, Isobel Fleming⁴

Affiliations

¹ Department of Medicine, Division of Geriatric Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. [email protected].
² Department of Medicine, Division of Geriatric Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
³ Team Lead, Drug Evaluation Unit, Department of Pharmacy, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.
⁴ Academic Detailing Service, Continuing Professional Development, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

PMID: 28198686
DOI: 10.3949/ccjm.84a.15114

Abstract

After performing a systematic review, members of the Palliative and Therapeutic Harmonization (PATH) program and the Dalhousie Academic Detailing Service found that evidence does not support lipid-lowering therapy for severely frail elderly patients.

Publication types

Review
Systematic Review

MeSH terms

Age Factors
Aged
Aged, 80 and over
Cardiovascular Diseases / drug therapy
Cardiovascular Diseases / etiology
Cardiovascular Diseases / prevention & control*
Contraindications, Drug*
Frail Elderly*
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
Hyperlipidemias / complications
Hyperlipidemias / drug therapy*
Hypolipidemic Agents / therapeutic use*
Primary Prevention
Quality of Life
Secondary Prevention

Substances

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypolipidemic Agents