Mild Lung Tuberculosis in a Patient Suffering from Status Epilepticus Caused by the Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)

Intern Med. 2017;56(4):429-433. doi: 10.2169/internalmedicine.56.7224. Epub 2017 Feb 15.

Abstract

A 76-year-old woman was diagnosed with lung tuberculosis. On the second day of anti-tuberculosis treatment, she became unconscious and developed status epilepticus accompanied by hyponatremia. The hyponatremia was caused by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Detailed examinations revealed that the patient's status epilepticus had occurred due to hyponatremia, which was caused by lung tuberculosis-associated SIADH. Previous case reports noted that patients with tuberculosis-associated SIADH showed mild clinical manifestations. They also reported that extensive lung involvement was associated with SIADH development. We herein report a rare case of SIADH complicated with status epilepticus that was caused by tuberculosis with mild lung involvement.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antitubercular Agents / therapeutic use
  • Female
  • Humans
  • Hyponatremia / etiology
  • Hyponatremia / microbiology
  • Inappropriate ADH Syndrome / complications*
  • Inappropriate ADH Syndrome / diagnosis
  • Inappropriate ADH Syndrome / microbiology
  • Radiography, Thoracic
  • Status Epilepticus / etiology*
  • Status Epilepticus / microbiology
  • Tomography, X-Ray Computed
  • Tuberculosis, Pulmonary / complications*
  • Tuberculosis, Pulmonary / diagnostic imaging
  • Tuberculosis, Pulmonary / drug therapy

Substances

  • Antitubercular Agents