A comprehensive Y-STR portrait of Yousafzai's population

Int J Legal Med. 2017 Sep;131(5):1241-1242. doi: 10.1007/s00414-017-1550-5. Epub 2017 Feb 16.

Abstract

In the current study, 17 Y-Chromosomal short tandem repeats (Y-STRs) included in theAmpFlSTR Y-Filer amplification kit (Applied Biosystems, Foster City, USA) were investigated in 146 unrelated Yousafzai males residing in the Khyber Pakhtunkhwa Province of Pakistan. A total of 94 (89.52%) unique haplotypes were observed. Discrimination capacity was 71.92%. Haplotype diversity ranged from 0.354 (DYS456) to 0.663 (DYS458). Both Rst pairwise analysis and multidimensional scaling plot showed that the genetic structure of the Yousafzais is significantly different from neighbouring populations.

Keywords: Forensic; Haplotype; Pakhtuns; Pakistan; Y-STR; Yousafzai.

MeSH terms

  • Chromosomes, Human, Y*
  • DNA Fingerprinting
  • Ethnicity / genetics*
  • Gene Frequency
  • Genetics, Population*
  • Haplotypes
  • Humans
  • Male
  • Microsatellite Repeats*
  • Pakistan
  • Polymerase Chain Reaction