Pulsatile iVAC 2L circulatory support in high-risk percutaneous coronary intervention

EuroIntervention. 2017 Feb 20;12(14):1689-1696. doi: 10.4244/EIJ-D-16-00371.

Abstract

Aims: Our aim was to test the feasibility and safety of the transfemoral PulseCath iVAC 2L (PulseCath, Amsterdam, The Netherlands).

Methods and results: Circulatory support devices are helpful adjunctive tools to perform high-risk percutaneous coronary interventions (PCI). The PulseCath iVAC 2L is a novel pulsatile circulatory support system capable of generating output of up to 2 L/min. We performed a prospective clinical pilot study enrolling 14 patients who underwent high-risk PCI under protection with the iVAC 2L. Median age was 74 (56-84) years. Implantation of the iVAC 2L was successful in 13 (93%) patients. Median device flow was 1.4 (1.1-2.0) L/min. Total support time was 67 (23-149) minutes. The use of iVAC 2L support was associated with a better mean arterial pressure and cardiac output during the procedure. Angiographic success was 100%. There was one major procedural complication related to the 19 Fr access sheath. There were no major adverse events at three-month follow-up.

Conclusions: Circulatory support with the iVAC 2L device is feasible and safe in patients undergoing high-risk PCI.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon, Coronary / instrumentation*
  • Angioplasty, Balloon, Coronary / methods
  • Coronary Artery Disease / therapy*
  • Female
  • Heart-Assist Devices*
  • Humans
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention* / methods
  • Pilot Projects
  • Prospective Studies
  • Prosthesis Design
  • Risk Assessment
  • Treatment Outcome