Perinatal outcomes after oocyte donation and in-vitro fertilization

Curr Opin Obstet Gynecol. 2017 Jun;29(3):126-130. doi: 10.1097/GCO.0000000000000356.

Abstract

Purpose of review: To critically appraise the existing literature on perinatal outcomes following oocyte donation (OD) pregnancies and compare it with autologous in-vitro fertilization (IVF) pregnancies.

Recent findings: OD pregnancies are at higher risk of developing hypertensive disorders compared with autologous IVF. The risk of preterm birth and low birth weight is higher with singleton and multiple OD compared with autologous IVF pregnancies. There is no increased risk of congenital malformations following OD compared with autologous IVF births.

Summary: OD pregnancies are at higher risk of developing hypertensive disorders and adverse perinatal outcomes compared with autologous IVF.

Publication types

  • Review

MeSH terms

  • Congenital Abnormalities
  • Female
  • Fertilization in Vitro*
  • Humans
  • Hypertension, Pregnancy-Induced
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Oocyte Donation*
  • Pregnancy
  • Pregnancy, Multiple
  • Premature Birth