1 aBiomedical Engineering Unit, First Department of Cardiology, Hippokration Hospital bDepartment of Hygiene, Epidemiology and Medical Statistics cCardiovascular Prevention and Research Unit, Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece dMenzies Institute for Medical Research, Tasmania, University of Tasmania, Hobart, Australia eCardiology Department, Klinikum Wels-Grieskirchen, Wels, Austria fFaculty of Medicine, Paris-Descartes University, Hôtel-Dieu Hospital, AP-HP, Diagnosis and Therapeutic Center, Paris, France gDivision of Internal Medicine; Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada hAustrian Institute of Technology, Health and Environment Department, Vienna, Austria iBrunel Institute for Bioengineering, Brunel University, Uxbridge, UK jLaboratory of Hemodynamics and Cardiovascular Technology, Institute of Biotechnology, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland kSchool of Medicine, Yale University, New Haven, Connecticut lDivision of Cardiovascular Medicine, University of Florida, Gainesville, Florida, USA.