HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4

J Allergy Clin Immunol. 2017 Aug;140(2):584-587.e8. doi: 10.1016/j.jaci.2016.11.049. Epub 2017 Mar 1.
No abstract available

Publication types

  • Letter

MeSH terms

  • Asthma / genetics
  • Asthma / metabolism*
  • Biomarkers
  • Enzyme-Linked Immunosorbent Assay
  • Gene Expression
  • HMGB1 Protein / genetics
  • HMGB1 Protein / metabolism*
  • Humans
  • Immunohistochemistry
  • Muscle Contraction*
  • Muscle, Smooth / metabolism*
  • Respiratory System / metabolism*
  • Sputum / metabolism
  • Toll-Like Receptor 4 / metabolism*

Substances

  • Biomarkers
  • HMGB1 Protein
  • HMGB1 protein, human
  • Toll-Like Receptor 4