Delayed-Onset Digital Ischemia After Local Anesthetic With Epinephrine Injection Requiring Phentolamine Reversal

J Hand Surg Am. 2017 Jun;42(6):479.e1-479.e4. doi: 10.1016/j.jhsa.2017.01.006. Epub 2017 Mar 1.

Abstract

The use of low-dose epinephrine in hand surgery has made it possible to perform a wide range of surgical procedures in the office setting. Low-dose epinephrine use is safe, and its vasoconstrictive effects are reversible with phentolamine. In this report, we present late-onset finger ischemia beginning 3 hours after an ipsilateral carpal tunnel and A1 pulley release of the middle finger anesthetized with local anesthetic and low-dose epinephrine (1:100,000). Finger ischemia lasted 14 hours until rescued with phentolamine injection.

Keywords: Anesthesia; carpal tunnel syndrome; digital ischemia; epinephrine; phentolamine.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anesthetics, Local
  • Antihypertensive Agents / therapeutic use*
  • Carpal Tunnel Syndrome / surgery
  • Epinephrine / adverse effects*
  • Female
  • Fingers / blood supply*
  • Humans
  • Ischemia / drug therapy
  • Ischemia / etiology*
  • Phentolamine / therapeutic use*
  • Postoperative Complications / drug therapy
  • Postoperative Complications / etiology
  • Vasoconstrictor Agents / adverse effects*

Substances

  • Anesthetics, Local
  • Antihypertensive Agents
  • Vasoconstrictor Agents
  • Epinephrine
  • Phentolamine