Phytochemical study and biological effects of the essential oil of Fraxinus dimorpha Coss & Durieu §

Nat Prod Res. 2017 Dec;31(23):2797-2800. doi: 10.1080/14786419.2017.1294173. Epub 2017 Feb 28.

Abstract

The present study describes the phytochemical study, antioxidant and antimicrobial activities of Fraxinus dimorpha essential oil, obtained from the leaves collected in the High Atlas Mountains. Forty compounds representing 86.2% with (E)-nerolidol as a major constituent and 29 compounds corresponding to 80.3% with eugenol as main components were identified from Ait M'hamed and from Siti Fadma, respectively. The F. dimorpha essential oil presents IC50 using DPPH varying from 5.33 to 6.03 mg/mL and EC50 using FRAP varying from 0.83 to 1.21 mg/mL. The antimicrobial activity of the oil was evaluated for ten microorganisms showed that the oil had a moderate potential activity. Fungal strains are more sensitive to the investigated oils, with a MIC varied between 1.8 and 3.8 mg/mL.

Keywords: F.dimorpha; antimicrobial activity; antioxidant activity; essential oil.

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Drug Evaluation, Preclinical / methods
  • Eugenol / analysis
  • Eugenol / pharmacology
  • Fraxinus / chemistry*
  • Inhibitory Concentration 50
  • Microbial Sensitivity Tests
  • Oils, Volatile / chemistry*
  • Oils, Volatile / pharmacology
  • Plant Leaves / chemistry
  • Sesquiterpenes / analysis
  • Sesquiterpenes / pharmacology

Substances

  • Anti-Infective Agents
  • Antioxidants
  • Oils, Volatile
  • Sesquiterpenes
  • Eugenol
  • nerolidol