Characterizing Sleep in Adolescents and Adults with Autism Spectrum Disorders

J Autism Dev Disord. 2017 Jun;47(6):1682-1695. doi: 10.1007/s10803-017-3089-1.

Abstract

We studied 28 adolescents/young adults with autism spectrum disorders (ASD) and 13 age/sex matched individuals of typical development (TD). Structured sleep histories, validated questionnaires, actigraphy (4 weeks), and salivary cortisol and melatonin (4 days each) were collected. Compared to those with TD, adolescents/young adults with ASD had longer sleep latencies and more difficulty going to bed and falling asleep. Morning cortisol, evening cortisol, and the morning-evening difference in cortisol did not differ by diagnosis (ASD vs. TD). Dim light melatonin onsets (DLMOs) averaged across participants were not different for the ASD and TD participants. Average participant scores indicated aspects of poor sleep hygiene in both groups. Insomnia in ASD is multifactorial and not solely related to physiological factors.

Keywords: Actigraphy; Adolescent Sleep Hygiene Scale; Adolescent Sleep Wake Scale; Cortisol; Melatonin.

Publication types

  • Observational Study

MeSH terms

  • Actigraphy / methods
  • Adolescent
  • Adult
  • Autism Spectrum Disorder / diagnosis*
  • Autism Spectrum Disorder / physiopathology
  • Autism Spectrum Disorder / psychology*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hydrocortisone* / analysis
  • Male
  • Melatonin* / analysis
  • Sleep / physiology
  • Sleep Initiation and Maintenance Disorders / diagnosis*
  • Sleep Initiation and Maintenance Disorders / physiopathology
  • Sleep Initiation and Maintenance Disorders / psychology*
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Melatonin
  • Hydrocortisone