Logopenic Aphasia due to a Strategic Stroke: New Evidence from a Single Case

J Alzheimers Dis. 2017;57(3):717-721. doi: 10.3233/JAD-161267.

Abstract

Among primary progressive aphasias (PPAs), logopenic variant PPA (lv-PPA) is usually related to Alzheimer's disease. Although it has been widely clinically and pathologically evaluated, the topography in LPA is still controversial. We report a patient presenting with a logopenic syndrome due to a strategic lesion located in the superior and middle temporal gyrus and compare our findings with those of a PiB-PET positive lv-PPA patient matched by age, gender, and education. We consider that our study provides new anatomical clues to better understand the cognitive mechanisms underlying the logopenic syndrome.

Keywords: Logopenic aphasia; primary progressive aphasia; stroke.

MeSH terms

  • Aphasia / diagnostic imaging
  • Aphasia / etiology*
  • Atrophy / etiology
  • Brain / diagnostic imaging
  • Brain / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Stroke / complications*
  • Stroke / diagnostic imaging