Abstract
We have been able to study the karyotypes and measure the DNA content in both the primary nonseminomatous germ cell tumor of the testes and the residual mature teratoma after chemotherapy of the same patient. Based on these and other studies, the mechanism of therapy-related differentiation in germ cell tumors of the testes is discussed.
Publication types
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Case Reports
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Chromosome Aberrations*
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DNA, Neoplasm / analysis
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Genetic Markers
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Humans
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Karyotyping
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Lung Neoplasms / secondary
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Male
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Neoplasms, Germ Cell and Embryonal / genetics*
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Neoplasms, Germ Cell and Embryonal / pathology
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Neoplasms, Germ Cell and Embryonal / therapy
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Retroperitoneal Neoplasms / genetics*
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Retroperitoneal Neoplasms / pathology
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Retroperitoneal Neoplasms / secondary
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Teratoma / genetics*
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Teratoma / pathology
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Teratoma / secondary
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Testicular Neoplasms / genetics*
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Testicular Neoplasms / pathology
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Testicular Neoplasms / therapy
Substances
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DNA, Neoplasm
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Genetic Markers