Extracorporeal photopheresis for the treatment of early-stage mycosis fungoides

Dermatol Ther. 2017 May;30(3). doi: 10.1111/dth.12485. Epub 2017 Mar 24.

Abstract

Extracorporeal photopheresis (ECP) has been used for nearly 30 years in the treatment of cutaneous T-cell lymphoma. However, current clinical practice largely reserves ECP for patients with late-stage mycosis fungoides (MF) or Sézary syndrome or for those who are refractory to other therapies. We briefly describe a 48-year-old male who experienced long-term complete remission of his patch MF disease with ECP, and we suggest a role for ECP in the treatment of early-stage MF given evidence of its efficacy, safety, and tolerability.

Keywords: Mycosis fungoides; Sézary syndrome; early stage; extracorporeal photopheresis.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Male
  • Middle Aged
  • Mycosis Fungoides / pathology
  • Mycosis Fungoides / therapy*
  • Photopheresis / methods*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy*
  • Treatment Outcome