Superficial herpes simplex virus wound infection following lung transplantation

Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12703. Epub 2017 May 15.

Abstract

Surgical site infections (SSIs) are infections of tissues, organs, or spaces exposed by surgeons during performance of an invasive procedure. SSIs are classified into superficial, which are limited to skin and subcutaneous tissues, and deep. The incidence of deep SSIs in lung transplant (LTx) patients is estimated at 5%. No reports have been published as to the incidence of superficial SSIs specifically in LTx patients. Common sense would dictate that the majority of superficial SSIs would be bacterial. Uncommonly, fungal SSIs may occur, and we believe that no reports exist as to the incidence of viral wound infections in LTx patients, or in any solid organ transplant patients. We report a de novo superficial wound infection with herpes simplex virus following lung transplantation, its possible source, treatment, and resolution.

Keywords: herpes simplex virus; lung transplantation; superficial wound infection.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antiviral Agents / therapeutic use*
  • Female
  • Ganciclovir / therapeutic use*
  • Herpes Simplex / diagnosis*
  • Herpes Simplex / drug therapy
  • Herpes Simplex / etiology
  • Herpes Simplex / virology
  • Humans
  • Lung Transplantation / adverse effects*
  • Simplexvirus / isolation & purification*
  • Surgical Wound Infection / diagnosis*
  • Surgical Wound Infection / drug therapy
  • Surgical Wound Infection / etiology
  • Surgical Wound Infection / virology
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Ganciclovir