[For a targeted use of aspirin]

Gynecol Obstet Fertil Senol. 2017 Apr;45(4):224-230. doi: 10.1016/j.gofs.2017.02.001. Epub 2017 Mar 23.
[Article in French]

Abstract

The use of low-dose aspirin in pregnancy should remain a highly targeted indication since its long-term safety has not been established and should be restricted to women at high risk of vascular complications. Indications for which the benefit of aspirin has been shown are women with a history of preeclampsia responsible for a premature birth before 34 weeks, those having at least two history of preeclampsia, those with an antiphospholipid syndrome and those with lupus associated with positive antiphospholipid antibodies or renal failure. In all other cases, the level of evidence of the benefit of aspirin is insufficient to recommend its routine prescription.

Keywords: Antiphospholipid antibody syndrome; Aspirin; Aspirine; Intrauterine growth restriction; Lupus; Preeclampsia; Pré-éclampsie; Retard de croissance intra-utérin; Syndrome des antiphospholipides.

MeSH terms

  • Abnormalities, Drug-Induced / etiology
  • Antiphospholipid Syndrome / complications
  • Antiphospholipid Syndrome / drug therapy
  • Aspirin / adverse effects*
  • Aspirin / therapeutic use*
  • Female
  • Humans
  • Pre-Eclampsia / drug therapy
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / drug therapy*
  • Premature Birth / prevention & control
  • Risk Factors

Substances

  • Aspirin