Endolichenic Fungi: A Hidden Reservoir of Next Generation Biopharmaceuticals

Brahma N Singh; Dalip K Upreti; Vijai K Gupta; Xiao-Feng Dai; Yueming Jiang

doi:10.1016/j.tibtech.2017.03.003

Endolichenic Fungi: A Hidden Reservoir of Next Generation Biopharmaceuticals

Trends Biotechnol. 2017 Sep;35(9):808-813. doi: 10.1016/j.tibtech.2017.03.003. Epub 2017 Mar 28.

Authors

Brahma N Singh¹, Dalip K Upreti², Vijai K Gupta³, Xiao-Feng Dai⁴, Yueming Jiang⁵

Affiliations

¹ Herbal Nanobiotechnology Lab, Pharmacognosy & Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow-226001, India. Electronic address: [email protected].
² Lichenology Laboratory, CSIR-National Botanical Research Institute, Lucknow-226001, India.
³ Department of Chemistry and Biotechnology, ERA Chair of Green Chemistry, Tallinn University of Technology, Tallinn, 12618, Estonia. Electronic address: [email protected].
⁴ Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
⁵ Key Laboratory of Plant Resource Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. Electronic address: [email protected].

PMID: 28363407
DOI: 10.1016/j.tibtech.2017.03.003

Abstract

Endolichenic fungi (ELF) offer an opportunity to discover emerging natural drugs. ELF are promising bioresources given their ability to produce bioactive metabolites that represent unique and diverse structural classes. Here, we assess the potential of recent technologies to provide insight into the chemical diversity of ELF for biopharmaceutical development.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biopharmaceutics
Drug Discovery*
Lichens / chemistry*