Fast assembling of neuron fragments in serial 3D sections

Brain Inform. 2017 Sep;4(3):183-186. doi: 10.1007/s40708-017-0063-9. Epub 2017 Apr 1.

Abstract

Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons.

Keywords: Alignment; Neuron; Neuron stitcher; Reconstruct morphology; Stitch; Vaa3D.