PDCD1LG2 (PD-L2) RNA in situ hybridization is a sensitive, specific, and practical marker of primary mediastinal large B-cell lymphoma

Br J Haematol. 2018 May;181(4):564-566. doi: 10.1111/bjh.14670. Epub 2017 Apr 3.

Authors

Zhen Wang¹, James R Cook¹

Affiliation

¹ Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

PMID: 28369778
DOI: 10.1111/bjh.14670

No abstract available

Keywords: diagnostic haematology; haematopathology; lymphoma; non-Hodgkin lymphoma.

Publication types

Letter

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor* / genetics
Biomarkers, Tumor* / metabolism
Female
Humans
In Situ Hybridization*
Lymphoma, Large B-Cell, Diffuse* / genetics
Lymphoma, Large B-Cell, Diffuse* / metabolism
Lymphoma, Large B-Cell, Diffuse* / pathology
Male
Mediastinal Neoplasms* / genetics
Mediastinal Neoplasms* / metabolism
Mediastinal Neoplasms* / pathology
Middle Aged
Neoplasm Proteins* / genetics
Neoplasm Proteins* / metabolism
Programmed Cell Death 1 Ligand 2 Protein* / genetics
Programmed Cell Death 1 Ligand 2 Protein* / metabolism
RNA, Messenger* / genetics
RNA, Messenger* / metabolism
RNA, Neoplasm* / genetics
RNA, Neoplasm* / metabolism

Substances

Biomarkers, Tumor
Neoplasm Proteins
PDCD1LG2 protein, human
Programmed Cell Death 1 Ligand 2 Protein
RNA, Messenger
RNA, Neoplasm