Type-2 Diabetes Mellitus and Oral Tumors in Hungary: A Long-term Comparative Epidemiological Study

Anticancer Res. 2017 Apr;37(4):1853-1857. doi: 10.21873/anticanres.11521.

Abstract

Background: Hungary has a leading place in global statistics of oral cancer and there is a high incidence of type-2 diabetes.

Patients and methods: A retrospective diabetes and impaired fasting glucose (IFG) screening of 758 inpatients with histologically-confirmed oral malignancies was performed. The control group comprised of 534 tumor-free adults. The results were compared to data collected 14 years earlier.

Results: Diabetes mellitus (DM) was found in 25.9% and IFG in 20.6% of patients with oral cancer. Fourteen years earlier, DM was diagnosed in 14.6% and IFG in 9.7% of cancer patients. Among diabetic patients, the labial tumor location showed long-term dominance. The smoking rate of diabetes patients with oral cancer was higher in the present than in the previous study.

Conclusion: The prevalence of type 2 diabetes and IFG increased significantly among oral cancer patients in the last 14 years.

Keywords: IFG; Type-2 diabetes; oral cancer; risk factor; smoking.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / epidemiology*
  • Carcinoma, Squamous Cell / etiology
  • Case-Control Studies
  • Diabetes Complications / epidemiology*
  • Diabetes Complications / etiology
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Female
  • Follow-Up Studies
  • Humans
  • Hungary / epidemiology
  • Male
  • Middle Aged
  • Mouth Neoplasms / epidemiology*
  • Mouth Neoplasms / etiology
  • Prevalence
  • Prognosis
  • Retrospective Studies
  • Risk Factors