Fluorescent Property of Chitosan Oligomer and Its Application as a Metal Ion Sensor

Mar Drugs. 2017 Apr 4;15(4):105. doi: 10.3390/md15040105.

Abstract

An aqueous solution was successfully prepared using a low-molecular-weight chitosan oligomer and FITC, and its structural and fluorescent properties were observed by using ¹H NMR, 13C NMR, FT-IR, XRD, UV-Vis, and PL spectrometry. Its application as a metal ion sensor was also evaluated. The fluorescence in the water-soluble chitosan oligomer was a result of the carbamato anion (NHCOO-), and a synthesized FITC-labeled chitosan oligomer exhibited an effective detection effect for copper ion as well as energy transfer by the ion near FITC that caused a fluorescence decrease (quenching). The chitosan oligomer was confirmed to be applicable as a selective and sensitive colorimetric sensor to detect Cu2+.

Keywords: chitosan oligomer; fluorescent property; metal ion sensor.

MeSH terms

  • Chitosan / chemistry*
  • Copper / chemistry
  • Energy Transfer / drug effects
  • Fluorescence
  • Fluorescent Dyes / chemistry*
  • Magnetic Resonance Imaging / methods
  • Metals / chemistry*
  • Spectrometry, Fluorescence / methods
  • Spectroscopy, Fourier Transform Infrared / methods
  • Water / chemistry

Substances

  • Fluorescent Dyes
  • Metals
  • water soluble chitin
  • Water
  • Copper
  • Chitosan