The role of neuropeptide W in energy homeostasis

Acta Physiol (Oxf). 2018 Jan;222(1). doi: 10.1111/apha.12884. Epub 2017 May 3.

Abstract

Neuropeptide W is the endogenous ligand for G-protein-coupled receptors GPR7 and GPR8. In this review, we summarize findings on the distribution of neuropeptide W and its receptors in the central nervous system and the periphery, and discuss the role of NPW in food intake and energy homeostasis.

Keywords: Neuropeptide W; central nervous system; energy homeostasis; food intake.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Eating / physiology
  • Energy Metabolism / physiology*
  • Homeostasis / physiology*
  • Humans
  • Neuropeptide Y / metabolism*

Substances

  • Neuropeptide Y