Genome Architecture from a Different Angle

Elizabeth H Finn; Tom Misteli

doi:10.1016/j.devcel.2017.03.017

Genome Architecture from a Different Angle

Dev Cell. 2017 Apr 10;41(1):3-4. doi: 10.1016/j.devcel.2017.03.017.

Authors

Elizabeth H Finn¹, Tom Misteli²

Affiliations

¹ National Cancer Institute, NIH, Bethesda, MD 20892, USA.
² National Cancer Institute, NIH, Bethesda, MD 20892, USA. Electronic address: [email protected].

Abstract

The study of genome architecture has recently been advanced by new techniques combining nuclear proximity ligation and high-throughput sequencing, but independent methods to validate them have been lacking. Reporting in Nature, Beagrie et al. (2017) describe such an orthogonal technique, called genome architecture mapping, to map genomes in 3D space.

Published by Elsevier Inc.

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MeSH terms

Chromosome Mapping*
Genome*
High-Throughput Nucleotide Sequencing

Grants and funding

ZIA BC010309-16/Intramural NIH HHS/United States