Objective: To explore the clinical application of home-made temporomandibular joint (TMJ) prostheses. Methods: Self-developed TMJ prostheses were applied for end stage osteoarthritis, TMJ ankylosis, condylar tumors after biomechanical examination. The stability of the prostheses toward bone was evaluated during operation. Post-operative CT scans and clinical follow-ups were taken to check changes of mouth opening, position of the prostheses, bone resorption around the screws, and heterotopic bone formation around artificial condyle. Results: There were 6 patients accepted 7 prostheses smoothly without infection and other complications. Post-operative follow-ups were from 6 to 13 months with a mean of 7.6 months. Mouth opening was significantly improved from (16.2±14.4) mm before operation to (31.5±4.8) mm during follow-ups (P=0.01). All prostheses were stable without screw loose and heterotopic bone formation. Conclusions: Home-made TMJ prostheses were stable after primary clinical application, but the long-term results need to be observed.
目的： 探讨自主研发的国产人工颞下颌关节的初步临床应用效果。 方法： 自主研发设计和制作人工颞下颌关节，经动物实验、生物力学等检测合格后，分别应用于晚期骨关节病、关节强直、髁突肿瘤患者的关节置换，术中评价假体与骨面的贴合程度和稳定性；术后进行CT检查和临床及影像学随访，观察患者的张口度、假体位置、螺钉周围有无骨吸收以及人工髁突周围有无异位成骨等，评价其初步临床应用效果。 结果： 6例患者7侧假体术中安装顺利，就位稳定，术后CT显示假体位置与手术设计无明显误差。术后随访6~13个月，平均7.6个月，术后张口度[（31.5±4.8）mm]与术前[（16.2±14.4）mm]相比显著增大（P=0.01），无感染等并发症发生，假体位置稳定、无螺钉松动移位、人工髁突周围无异位成骨。 结论： 自主研发的国产人工颞下颌关节假体通过初步临床应用效果稳定，远期效果需要进一步观察。.
Keywords: Home-made; Joint prosthesis; Temporomandibular joint; Therapeutic uses.