Primary amyloidosis of the urinary bladder is a rare disease, with only approximately 200 cases reported in the literature. We herein present a case of amyloidosis of the urinary bladder with painful gross hematuria. Pelvic Computed Tomography showed uneven thickening of the bladder wall suspicious of neoplastic lesion. Cystoscopy and transurethral resection were performed. Congo-red staining confirmed amyloidosis it was. Postoperative recovery was good and close follow-up was recommended after discharged. Amyloidosis is usually benign, while it can masquerade as a malignancy. Doctors should consider it when imaging studies reveal a malignancy in bladder.
Keywords: Amyloidosis; Hematuria; Transurethral resection.