Influence of demographic characteristics on attenuated positive psychotic symptoms in a young, help-seeking, at-risk population

Early Interv Psychiatry. 2019 Feb;13(1):53-56. doi: 10.1111/eip.12444. Epub 2017 Apr 18.

Abstract

Aim: Presentation of attenuated positive psychotic symptoms (APS) was reported to be modestly influenced by age, sex and education in a psychosis-risk sample. We re-examined the influence of demographic variables on APS in an independent psychosis-risk sample.

Method: In a clinical high-risk-sample (N = 188; 13-35 years; 60.1% men), bivariate correlations were examined with Spearman correlations. All other associations were computed with generalized linear models.

Results: Inter-correlations between positive symptoms were statistically significant for all but the smallest coefficient (range: r = 0.12-0.49). Age was negatively related to APS (range: OR = 0.53-0.78, all P < .01). Male sex was uniquely related to disorganized communication (OR = 1.46) and a high education-level related negatively to suspiciousness/persecutory ideas (OR = 0.64), perceptual abnormalities/hallucinations (OR = 0.57) and disorganized communication (OR = 0.54). The variance explained by age ranged from R 2 = 0.044 for unusual thought content to R 2 = 0.144 for perceptual abnormalities.

Conclusion: Our results highlighted the role of age and, thereby, neurodevelopment in psychosis-risk assessment.

Keywords: age; clinical-high-risk; early recognition; psychosis; sex.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Demography
  • Female
  • Humans
  • Male
  • Prodromal Symptoms
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / epidemiology*
  • Psychotic Disorders / psychology*
  • Risk Factors
  • Sex Factors
  • Young Adult