Antiretroviral Therapy Initiation and Changes in Self-Reported Depression

Clin Infect Dis. 2017 Jun 15;64(12):1791-1794. doi: 10.1093/cid/cix217.

Abstract

In this retrospective study of treatment-naive PLWH initiating antiretroviral therapy, the score for the depression scale of the Patient Health Questionnaire (PHQ-9) was significantly higher at baseline (median, 6.0; interquartile range, 2-11) than at 12 months (3.0; 0-8; P < .001). Baseline depression and lack of insurance are associated with 12-month depression, but receipt of efavirenz-based antiretroviral therapy is not.

Keywords: ART; HIV; depression; efavirenz; patient-centered..

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Alkynes
  • Anti-HIV Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active*
  • Benzoxazines / therapeutic use
  • Cyclopropanes
  • Depression / complications*
  • Depression / epidemiology
  • Follow-Up Studies
  • HIV Infections / drug therapy*
  • HIV Infections / psychology*
  • Humans
  • Insurance, Health
  • Logistic Models
  • Male
  • Middle Aged
  • Retrospective Studies
  • Self Report
  • Young Adult

Substances

  • Alkynes
  • Anti-HIV Agents
  • Benzoxazines
  • Cyclopropanes
  • efavirenz