Predictive Protein Toxicity and Its Use in Risk Assessment

Niccolò Franceschi; Konstantinos Paraskevopoulos; Elisabeth Waigmann; Matthew Ramon

doi:10.1016/j.tibtech.2017.03.010

Predictive Protein Toxicity and Its Use in Risk Assessment

Trends Biotechnol. 2017 Jun;35(6):483-486. doi: 10.1016/j.tibtech.2017.03.010. Epub 2017 Apr 15.

Authors

Niccolò Franceschi¹, Konstantinos Paraskevopoulos¹, Elisabeth Waigmann¹, Matthew Ramon²

Affiliations

¹ European Food Safety Authority (EFSA), Via Carlo Magno 1A, 43126 Parma, Italy.
² European Food Safety Authority (EFSA), Via Carlo Magno 1A, 43126 Parma, Italy. Electronic address: [email protected].

PMID: 28420532
DOI: 10.1016/j.tibtech.2017.03.010

Abstract

In the EU novel proteins used in food or feed are assessed for their potential toxic effects in humans and livestock animals. The discovery of clear molecular features linked to the toxicity of a protein may be an important step towards the use of predictive protein toxicity in risk assessment.

Keywords: domains; molecular signatures; motifs; novel food and feed proteins; protein toxicity; risk assessment.

Publication types

Review

MeSH terms

Animal Feed / toxicity*
Animals
Dietary Proteins / toxicity*
Food Analysis / methods*
Humans
Risk Assessment

Substances

Dietary Proteins