Metabolic syndrome and its components are related to psychological disorders: A population based study

Background: Psychological disorders are considered as today's one of the most important public health problems all around the world. Another alarming condition, which attributed to cardiovascular disease (CVD) is metabolic syndrome (Mets). The aims of the current study were to explore (1) the prevalence of anxiety and depression in a large representative population of Iran, and (2) evaluate their possible association with MetS patients.

Method: Applying a randomized stratified-cluster approach, 9829 adults, aged 35-65 years, were recruited as part of the MASHAD study. Socio demographic, anthropometric and biochemical analyses were performed. Beck's anxiety inventory and Beck's depression inventory II were applied to assessment of the degree of anxiety and depression among the subjects.

Results: The prevalence of MetS, anxiety and depression were 38.8%, 25% and 31.5%, respectively. The prevalence of these factors was significantly (P<0.05) higher in women, compared to men and subjects with MetS were significantly (P<0.05) associated with both anxiety and depression. Additionally, multivariate analysis after adjusting for potential confounders showed a significant relationship between MetS and anxiety (p=0.04).

Conclusion: Our data demonstrates the significant association of MetS components with anxiety and depression and high prevalence of these co-morbidities in adults, particularly in women.