Efficacy of fluoride varnishes for preventing enamel demineralization after interproximal enamel reduction. Qualitative and quantitative evaluation

PLoS One. 2017 Apr 21;12(4):e0176389. doi: 10.1371/journal.pone.0176389. eCollection 2017.

Abstract

Objectives: To evaluate quantitatively and qualitatively the changes produced to enamel after interproximal reduction and subjected to demineralization cycles, after applying a fluoride varnish (Profluorid) and a fluoride varnish containing tricalcium phosphate modified by fumaric acid (Clinpro White).

Materials and methods: 138 interproximal dental surfaces were divided into six groups: 1) Intact enamel; 2) Intact enamel + demineralization cycles (DC); 3) Interproximal Reduction (IR); 4) IR + DC; 5) IR + Profluorid + DC; 6) IR + Clinpro White + DC. IR was performed with a 0.5 mm cylindrical diamond bur. The weight percentage of calcium (Ca), phosphorous (P) and fluoride (F) were quantified by energy-dispersive X-ray spectrometry (EDX). Samples were examined under scanning electron microscopy (SEM).

Results: The weight percentage of Ca was significantly higher (p<0.05) in Groups 1, 2 and 5 than Groups 4 and 6. No significant differences were detected in the weight percentage of Ca between Group 3 and the other groups (p>0.05). The weight percentage of P was similar among all six groups (p>0.05). F was detected on 65% of Group 6 surfaces. SEM images of Groups 4 and 6 showed signs of demineralization, while Group 5 did not.

Conclusions: Profluorid application acts as a barrier against the demineralization of interproximally reduced enamel.

MeSH terms

  • Fluorides, Topical / administration & dosage*
  • Fluorides, Topical / adverse effects
  • Humans
  • Microscopy, Electron, Scanning
  • Qualitative Research
  • Spectrometry, X-Ray Emission
  • Tooth Demineralization / chemically induced*

Substances

  • Fluorides, Topical

Grants and funding

The authors received no specific funding for this work.