Successful Treatment of Stable Vitiligo by Low-Density Cultured Autologous Melanocyte Transplantation Combined With Narrowband Ultraviolet B Therapy

Dermatol Surg. 2017 Oct;43(10):1281-1287. doi: 10.1097/DSS.0000000000001174.

Abstract

Background: Cultured autologous melanocyte transplantation (CMT) is an effective treatment for stable vitiligo, but the current method is time consuming and expensive because of the requirement of a large number of melanocytes.

Objective: To assess the clinical effect of low-density CMT combined with narrowband ultraviolet B (NB-UVB) in treating stable vitiligo.

Materials and methods: The authors treated 8 patients with CMT at a low cell density (less than 2.5 × 10 cells/cm). Among them, 6 patients underwent NB-UVB therapy after CMT.

Results: All the 6 patients treated with low-density CMT combined with NB-UVB obtained more than 90% repigmentation at the 1-year follow-up.

Conclusion: The authors' data suggest that low-density CMT combined with NB-UVB can be an effective form of surgical treatment for stable vitiligo.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child
  • Combined Modality Therapy
  • Female
  • Humans
  • Male
  • Melanocytes / transplantation*
  • Remission Induction
  • Transplantation, Autologous
  • Ultraviolet Therapy*
  • Vitiligo / radiotherapy*
  • Vitiligo / surgery*
  • Young Adult