Ablative surgery for Parkinson's disease: Is there still a role for pallidotomy in the deep brain stimulation era?

Clin Neurol Neurosurg. 2017 Jul:158:33-39. doi: 10.1016/j.clineuro.2017.04.018. Epub 2017 Apr 23.

Abstract

Posteroventral pallidotomy has already been considered the surgical procedure of choice for Parkinson's disease patients with motor complications. Recently, however, several factors led to its replacement by deep brain stimulation. Nevertheless, pallidotomy has a well-documented efficacy and safety evidence regarding the reduction of parkinsonian motor symptoms. Yet, there may be manysituations where it may be considered as a better option than neuromodulation. Herein we review those possible conditions, giving emphasis to the costs, which we found to be the most limiting factor. Importantly, a cost comparison between deep brain stimulation and pallidotomy was also provided.

Keywords: Ablation; Deep brain stimulation; Pallidotomy; Parkinson’s disease.

Publication types

  • Review

MeSH terms

  • Ablation Techniques* / economics
  • Ablation Techniques* / methods
  • Ablation Techniques* / standards
  • Deep Brain Stimulation* / economics
  • Deep Brain Stimulation* / methods
  • Deep Brain Stimulation* / standards
  • Humans
  • Pallidotomy* / economics
  • Pallidotomy* / methods
  • Pallidotomy* / standards
  • Parkinson Disease / surgery*