Construction and application of plasmids containing bidirectional promoters of vaccinia virus

J Virol. 1988 Dec;62(12):4832-4. doi: 10.1128/JVI.62.12.4832-4834.1988.

Abstract

A bidirectional expression vector containing both the 11KD late promoter (p11) and the presumptive 25KD early promoter (p25) was constructed. These bidirectional vectors have been applied to the expression of hepatitis B surface antigen by using one of the promoters for beta-galactosidase as the marker gene and the other one for hepatitis B surface antigen as the target gene.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Restriction Enzymes
  • Gene Expression Regulation*
  • Genetic Markers
  • Genetic Vectors*
  • Hepatitis B Surface Antigens / genetics
  • Plasmids*
  • Promoter Regions, Genetic*
  • Vaccinia virus / genetics*
  • beta-Galactosidase / genetics

Substances

  • Genetic Markers
  • Hepatitis B Surface Antigens
  • DNA Restriction Enzymes
  • beta-Galactosidase