Cutaneous Pseudolymphoma

Surg Pathol Clin. 2017 Jun;10(2):455-476. doi: 10.1016/j.path.2017.01.002. Epub 2017 Mar 22.

Abstract

The term, cutaneous pseudolymphoma (PSL), refers to a group of lymphocyte-rich infiltrates, which either clinically and/or histologically simulate cutaneous lymphomas. Clinicopathologic correlation is essential to achieve the final diagnosis in cutaneous PSL and to differentiate it from cutaneous lymphomas. A wide range of causative agents (eg, Borrelia, injections, tattoo, and arthropod bite) has been described. Based on clinical and/or histologic presentation, 4 main groups of cutaneous PSL can be distinguished: (1) nodular PSL, (2) pseudo-mycosis fungoides, (3) other PSLs (representing distinct clinical entities), and (4) intravascular PSL. The article gives an overview of the clinical and histologic characteristics of cutaneous PSLs.

Keywords: B-cell; Borreliosis; Cutaneous pseudolymphoma; Histology; T-cell; Tattoo.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Humans
  • Lymphoma, B-Cell
  • Mycosis Fungoides / pathology
  • Pseudolymphoma / pathology*
  • Skin Diseases / pathology*
  • Skin Neoplasms / pathology