Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6

J Allergy Clin Immunol. 2017 Oct;140(4):1172-1176.e3. doi: 10.1016/j.jaci.2017.04.018. Epub 2017 May 4.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkalies
  • Animals
  • Caspase 8 / immunology*
  • Dry Eye Syndromes / immunology*
  • Eye Burns / chemically induced
  • Eye Burns / immunology*
  • Mice, Inbred C57BL
  • NLR Family, Pyrin Domain-Containing 3 Protein / immunology*
  • Receptors, Cell Surface / immunology*
  • Stress, Physiological

Substances

  • Alkalies
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • Nlrp3 protein, mouse
  • Nod-like receptor pyrin domain-containing protein 6, mouse
  • Receptors, Cell Surface
  • Caspase 8