Variation in plasma cytokine concentration during a training season in elite kayakers

J Sports Med Phys Fitness. 2018 Oct;58(10):1519-1524. doi: 10.23736/S0022-4707.17.07202-4. Epub 2017 May 5.

Abstract

Background: The purpose of this study was to investigate the differences in cytokines levels in the peripheral blood of kayakers at different moments of training.

Methods: The sample comprised 12 elite kayakers preparing for the Beijing Olympic Games. Blood samples were collected at different time points of the training season: baseline (t0-November) after 6 weeks of off-training and before the start of the training season; t1 (January) at week 11 after a period of high-volume training; t2 (April) at week 26 at the end of a period of high intensity training sessions; t3 (June) at week 31 after a competitive period.

Results: Decreases in cytokine levels were found for IL-1β and IL-18 at t1. IL-1 then increased throughout the remaining training season while IL-18 leveled off towards the end of the season. IL-1ra showed an exponential increase at t2 before leveling-off in the last period of training. No significant changes were found for IL-6, IFN-γ and TNF-α. No differences were observed in the magnitude and pattern of cytokines changes across the training season between the elite female and male kayakers.

Conclusions: Increases in training volume were able to induce decreases in pro-inflammatory plasma cytokine coinciding with the reported increase in upper respiratory tract infections in the kayakers.

MeSH terms

  • Adolescent
  • Adult
  • Athletes
  • Cytokines / blood*
  • Female
  • Humans
  • Interferon-gamma
  • Interleukin-18
  • Interleukin-1beta
  • Interleukin-6
  • Male
  • Physical Conditioning, Human*
  • Respiratory Tract Infections / epidemiology
  • Time Factors
  • Tumor Necrosis Factor-alpha
  • Water Sports / physiology*
  • Young Adult

Substances

  • Cytokines
  • IFNG protein, human
  • IL1B protein, human
  • IL6 protein, human
  • Interleukin-18
  • Interleukin-1beta
  • Interleukin-6
  • Tumor Necrosis Factor-alpha
  • Interferon-gamma