Aim: The halichondrin B analog, eribulin, exerts an anticancer effect, as reported by several clinical and real-life studies on metastatic breast cancer patients. Here, we evaluated efficacy and safety of eribulin, focusing on response to treatment per metastasis type.
Patients & methods: This monocentric, real-life study was conducted on 31 heavily pretreated patients with metastatic breast cancer.
Results: The median progression-free survival and overall survival were 2.0 and 5.5 months, respectively. All patients (12.9%) responding to eribulin were treated in fourth-line setting. Considering response per metastasis type, bone lesions (13.6%) responded more frequently than other metastases to eribulin.
Conclusion: Eribulin exhibited a good overall response rate, with the highest response observed for bone metastases.
Keywords: eribulin; metastatic breast cancer; response; type of metastatic site.