Karyotyping and DNA flow cytometry of an orchidoblastoma

J W Oosterhuis; S M Castedo; B de Jong; R Seruca; J Buist; H Schraffordt Koops; J B Leeuw

doi:10.1016/0165-4608(88)90069-6

Karyotyping and DNA flow cytometry of an orchidoblastoma

Cancer Genet Cytogenet. 1988 Nov;36(1):7-11. doi: 10.1016/0165-4608(88)90069-6.

Authors

J W Oosterhuis¹, S M Castedo, B de Jong, R Seruca, J Buist, H Schraffordt Koops, J B Leeuw

Affiliation

¹ Department of Pathology, State University of Groningen, The Netherlands.

PMID: 2849502
DOI: 10.1016/0165-4608(88)90069-6

Abstract

The first karyotype of an orchidoblastoma is described. The most striking finding is the absence of the i(12p) marker chromosome, considered specific for testicular germ cell tumors of adults. Differences between infantile and adult testicular germ cell tumors are discussed, as are features that infantile testicular germ cell tumors have in common with extragonadal germ cell tumors.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Age Factors
Chromosome Aberrations*
DNA, Neoplasm / analysis
Flow Cytometry
Humans
Infant
Karyotyping
Male
Mesonephroma / genetics
Mesonephroma / pathology
Neoplasms, Germ Cell and Embryonal / genetics*
Neoplasms, Germ Cell and Embryonal / pathology
Testicular Neoplasms / genetics*
Testicular Neoplasms / pathology

Substances

DNA, Neoplasm