Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis

Ann Rheum Dis. 2018 Apr;77(4):626-628. doi: 10.1136/annrheumdis-2016-210834. Epub 2017 May 11.
No abstract available

Keywords: Autoimmune Diseases; Fibroblasts; Systemic Sclerosis.

Publication types

  • Evaluation Study
  • Letter
  • Multicenter Study

MeSH terms

  • Aged
  • Case-Control Studies
  • Female
  • Fibrosis
  • Fingers
  • Hedgehog Proteins / blood*
  • Humans
  • Hypertension, Pulmonary / etiology
  • Male
  • Middle Aged
  • Scleroderma, Systemic / blood*
  • Scleroderma, Systemic / complications
  • Scleroderma, Systemic / pathology
  • Skin / pathology*
  • Skin Ulcer / etiology

Substances

  • Hedgehog Proteins
  • SHH protein, human