Intestinal Transplant in Children

Nidhi Rawal; Nada Yazigi

doi:10.1016/j.pcl.2017.02.002

Intestinal Transplant in Children

Pediatr Clin North Am. 2017 Jun;64(3):613-619. doi: 10.1016/j.pcl.2017.02.002.

Authors

Nidhi Rawal¹, Nada Yazigi²

Affiliations

¹ Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Maryland Medical Center, 22 South Green Street, Baltimore, MD 21201, USA.
² Pediatric Transplant Hepatology, Department of Transplantation, MedStar Georgetown University Hospital, MedStar Georgetown Transplant Institute, PHC#2, 3800 Reservoir Road, Northwest, Washington, DC 20007, USA. Electronic address: [email protected].

PMID: 28502441
DOI: 10.1016/j.pcl.2017.02.002

Abstract

The past decade has seen major advances in the field of transplantation; it is the treatment of choice for many with intestinal failure. One-year mortality from pediatric intestinal transplantation has significantly declined, from 30% to 10% to 15% nationally, mainly due to a multidisciplinary approach in transplant centers. Pediatric age carries special considerations along the spectrum of care that continue to cause challenges but also offers growth opportunities. Pediatric intestinal transplantation indications and timing are changing as a result of new developments in diagnostic and treatment tools. This article reviews updates on pediatric intestinal transplantation and highlights future directions.

Keywords: Intestine; Pediatric; Short gut syndrome; Transplant.

Publication types

Review

MeSH terms

Child
Humans
Intestinal Diseases / surgery*
Intestines / transplantation*
Organ Transplantation / adverse effects
Organ Transplantation / methods*
Organ Transplantation / mortality
Pediatrics
Survival Rate
Treatment Outcome