Introduction: The 23rd Annual Prostate Cancer Foundation (PCF) Scientific Retreat was convened October 27-29, 2016, in Carlsbad, CA.
Methods: This event focuses on the latest advances in basic, translational, and clinical prostate cancer research with the greatest promise for advancing our understanding of prostate cancer biology and improving patient outcomes and quality of life.
Results: Themes highlighted at this year's meeting included: i) targeting DNA repair deficiency in prostate cancer; ii) optimizing the use of Radium-223 and bone-targeting agents; iii) advances in cancer immunotherapeutic approaches; iv) targeting developmental pathways in prostate cancer; v) advances in circulating tumor DNA technology and applications; vi) precision survivorship; and vii) novel treatments and treatment strategies in prostate cancer.
Discussion: This article reviews the key advances discussed at the Retreat for the purpose of disseminating this knowledge to accelerate the development of new treatments and improved outcomes for men suffering with prostate cancer.
Keywords: androgen receptor; diagnosis; prognosis; therapy; tumor biology.
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