NF-κB p50 (nfkb1) contributes to pathogenesis in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia

Blood. 2017 Jul 20;130(3):376-379. doi: 10.1182/blood-2017-01-761130. Epub 2017 May 17.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging, Premature / genetics
  • Animals
  • Crosses, Genetic
  • Disease Models, Animal
  • Gene Expression Regulation, Leukemic
  • Leukemia, Lymphocytic, Chronic, B-Cell / blood
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / pathology
  • Leukocyte Count
  • Mice
  • Mice, Knockout
  • NF-kappa B p50 Subunit / deficiency
  • NF-kappa B p50 Subunit / genetics
  • NF-kappa B p50 Subunit / physiology*
  • Neoplasm Proteins / blood
  • Neoplasm Proteins / genetics
  • Organ Size
  • Proto-Oncogene Proteins / biosynthesis
  • Proto-Oncogene Proteins / genetics
  • Spleen / pathology
  • Tumor Burden

Substances

  • NF-kappa B p50 Subunit
  • Neoplasm Proteins
  • Proto-Oncogene Proteins
  • Tcl1 protein, mouse
  • Nfkb1 protein, mouse